Fwd: Perspectives on hormone replacement therapy: the Women's Health Initiative and new observational studies sampling the overall population.

---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Sun, Aug 3, 2008 at 8:08 AM
Subject: Perspectives on hormone replacement therapy: the Women's Health Initiative and new observational studies sampling the overall population.
To: mesothelioma77@gmail.com


[1]Fertil Steril. 2008 Aug; 90(2): 258-64
Tannen RL, Weiner MG, Xie D, Barnhart K

This commentary integrates the most recent information on coronary heart disease from the Women's Health Initiative (WHI) trial and our new large observational studies, which complement and expand the WHI results to the overall population. Breast and colon cancer findings are also considered.



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Source: http://www.hubmed.org/display.cgi?uids=18672122
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Fwd: Breast cancer stem cells: implications for therapy of breast cancer.

---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Sun, Aug 3, 2008 at 8:08 AM
Subject: Breast cancer stem cells: implications for therapy of breast cancer.
To: mesothelioma77@gmail.com


[1]Breast Cancer Res. 2008 Jul 22; 10(4): 210
Morrison BJ, Schmidt CW, Lakhani SR, Reynolds BA, Lopez JA

ABSTRACT: The concept of cancer stem cells responsible for tumour origin, maintenance, and resistance to treatment has gained prominence in the field of breast cancer research. The therapeutic targeting of these cells has the potential to eliminate residual disease and may become an important component of a multimodality treatment. Recent improvements in immunotherapy targeting of tumour-associated antigens have advanced the prospect of targeting breast cancer stem cells, an approach that might lead to more meaningful clinical remissions. Here, we review the role of stem cells in the healthy breast, the role of breast cancer stem cells in disease, and the potential to target these cells.



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Source: http://www.hubmed.org/display.cgi?uids=18671830
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